Which Injection Sites Are Used for Mounjaro and Wegovy?
Both Mounjaro (tirzepatide) and Wegovy (semaglutide) are once-weekly subcutaneous injections — meaning they are delivered into the fatty tissue just beneath the skin, not into muscle. According to product information available on the electronic Medicines Compendium, the recommended sites are the abdomen (avoiding the area immediately around the navel), the front of the thigh, and the upper arm.
Why rotation matters
Using the same spot repeatedly can cause localised skin changes — sometimes called lipohypertrophy — which may affect how the medicine is absorbed. Most healthcare professionals advise rotating sites with each injection: for example, left abdomen one week, right thigh the next. Within a single site, slightly varying the exact spot also helps.
Is one site better than another?
In general, all three sites are considered suitable — there is no universal "best" spot, and individual preference, comfort, and body composition all play a role. Many people find the abdomen easiest to reach and pinch; others prefer the thigh. If you have a preference or a concern about a particular site, your prescriber or doctor is the right person to advise based on your individual situation.
For a closer look at the equipment involved in each weekly injection, the guide to pens and accessories for Mounjaro covers what to expect. You may also find it useful to read the broader overview on managing your Mounjaro journey for context on how injection habits fit into the wider routine.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Tracking Injection Sites with GLP Trackr
Keeping a mental note of which site you used last week is surprisingly easy to forget — especially across a long titration schedule. GLP Trackr's injection-site tracking and rotation feature is built precisely for this: each time you log a dose, you record the site you used, and the app tracks your rotation history so it can suggest where to inject next. There is no guesswork and no trying to remember whether it was the left or right side a week ago.
Alongside site tracking, the app logs the dose strength and date of every injection, giving you a clear, timestamped record of your full treatment history. That record is genuinely useful to bring to prescriber appointments — particularly if you want to discuss how you have been getting on or whether any injection-site reactions have occurred.
If you are also thinking about where to source your prescription, the page on accessing Mounjaro through a prescriber explains the general process, while injection site tips and rotation guidance goes deeper on the practical side of rotating sites week to week.
GLP Trackr helps you record this so you can discuss it with your prescriber — it is not a substitute for their advice. If you notice persistent redness, swelling, or any skin change at an injection site, contact your healthcare professional promptly rather than waiting for your next scheduled appointment.
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Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
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Frequently asked questions.
The three recommended subcutaneous injection sites are the abdomen, the front of the thigh, and the upper arm. All are considered suitable; the best choice for you depends on your individual comfort and your prescriber's guidance. Refer to the patient information leaflet that came with your pen.
Yes — rotating sites with each weekly injection is widely recommended. Using the same spot repeatedly can cause skin changes that may affect absorption. Alternating between the abdomen, thigh, and upper arm, and varying the exact spot within each area, helps keep skin healthy.
Consistently using a single spot is generally not advised, as it may lead to localised skin changes. If you have concerns about which sites work best for you, speak with your prescriber or doctor — they can offer guidance tailored to your situation.
GLP Trackr logs each injection with the site you used and tracks your rotation history, then suggests where to inject next. It also records the dose strength and date, creating a full treatment log you can share with your prescriber.
Contact your healthcare professional promptly if you notice persistent redness, swelling, hardness, or any unusual skin change at an injection site. Do not wait for a routine appointment — your prescriber or doctor can advise on whether to avoid that site and what steps to take.