What changing from Mounjaro to Wegovy actually means
Mounjaro (tirzepatide) and Wegovy (semaglutide) are both once-weekly injectable medicines used for weight management, but they work differently. Mounjaro acts on two receptors — GLP-1 and GIP — while Wegovy acts on GLP-1 alone. Both are prescription-only and are taken via pre-filled injection pens, but they have different dose strengths, titration schedules, and pen designs.
Because the two medicines are not equivalent in dose or mechanism, a switch is not a simple like-for-like swap. Your prescriber will typically decide the starting dose for the new medicine based on your individual situation — it is common to begin at a lower dose when starting any new GLP-1 medicine, but your prescriber will advise what is right for you specifically.
Why someone might switch
There are several reasons a prescriber might consider a change between these medicines. These can include tolerability, availability, a change in clinical guidance, or a reassessment of what is appropriate for a particular person. If you are wondering whether switching is right for you, the right starting point is a conversation with your prescriber — not a decision made independently.
For a closer look at the practical and clinical considerations involved, see our pages on whether you can change from Mounjaro to Wegovy and what changing from Mounjaro to Wegovy involves. You may also find it useful to read about the Mounjaro to Wegovy transition more broadly.
For general information about Mounjaro, visit our Mounjaro guide.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Tracking your journey through a medicine change with GLP Trackr
A switch between medicines is a moment when consistent tracking becomes especially valuable. GLP Trackr's dose logging feature lets you record each injection — the medicine name, dose strength, date, and time — so you have a clear, timestamped record of exactly when you moved from one medicine to the other. This kind of log can be genuinely useful to bring to your next prescriber appointment.
If you notice changes in how you feel after switching — different side-effect patterns, shifts in appetite or energy — the side-effect and daily check-in tracking in GLP Trackr lets you log those experiences and spot trends over time. Having that record means you can describe what you have actually experienced, rather than relying on memory, when you speak to your healthcare professional.
Any decision about your dose — including what dose to start on after a switch — should be made with your prescriber, never independently. GLP Trackr helps you record and reflect on your journey; it is not a substitute for clinical guidance.
If you are starting a new medicine or a new dose stage, keeping a consistent log from day one means you build a clear picture of how things are going. Download GLP Trackr on the App Store or Google Play and explore it free for your first 7 days.
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Morning Check-In
Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
Injection Tracking
Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
Hydration Reminders
Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
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Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
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Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.
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Frequently asked questions.
It is possible to switch between these medicines, but only with guidance from your prescriber or doctor. They will assess your individual situation before recommending any change. Switching is not a decision to make independently, as the two medicines work differently and have different dose schedules.
The starting dose after a switch is determined by your prescriber based on your individual history and clinical assessment. Mounjaro and Wegovy are not dose-equivalent, so your prescriber — not a general guideline — is the right source of advice on this.
Some people notice changes in side-effect patterns when moving between GLP-1 medicines, since the two drugs have different mechanisms. What you experience is individual. If you notice anything new or concerning after a switch, contact your healthcare professional promptly.
GLP Trackr lets you log each dose — including the medicine name, strength, date, and time — so you have a clear record of when the switch happened. You can also log side effects and daily wellbeing to build a picture that is useful to share with your prescriber.
The timing of stopping one medicine and starting another is a clinical decision for your prescriber. Never stop or start a prescription medicine without their guidance. Your prescriber will advise on the appropriate approach for your specific situation.