How Mounjaro and Wegovy Differ: Active Substance and Mechanism
Both medicines target appetite-regulating pathways, but they do so in different ways.
Wegovy (semaglutide)
Wegovy contains semaglutide, a GLP-1 receptor agonist. GLP-1 (glucagon-like peptide-1) is a hormone involved in regulating appetite and feelings of fullness. By activating GLP-1 receptors, semaglutide is commonly reported to reduce appetite and slow gastric emptying. Dose strengths typically referenced are 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg, started low and adjusted over time by the prescriber.
Mounjaro (tirzepatide)
Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist. In addition to the GLP-1 pathway, it also activates GIP (glucose-dependent insulinotropic polypeptide) receptors. Dose strengths commonly referenced are 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. As with Wegovy, titration is always guided by the prescriber. For a closer look at the specific distinctions, see how Mounjaro and Wegovy compare in detail or explore the differences between Wegovy and Mounjaro from a Wegovy perspective.
What they have in common
- Both are prescription-only, once-weekly injectable medicines
- Both are supplied as pre-filled pens
- Both are subject to additional monitoring — report any side effects to your healthcare professional and to your national reporting scheme (such as the UK's Yellow Card scheme)
- Neither is suitable for everyone; suitability is determined by a prescriber
- Neither is a substitute for dietary changes, physical activity, or clinical supervision
If you are already on Mounjaro and want to understand the differences between its dose strengths, the page on the difference between 2.5 mg and 5 mg Mounjaro covers that in detail.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
Tracking the right four numbers — weight, waist, protein and dose — turns a noisy chart into a clear story. That's the loop GLP-1 users keep coming back for.
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Whichever Injection You Are On, GLP Trackr Tracks It
GLP Trackr is built for people already prescribed either medicine, and it supports both Mounjaro and Wegovy users equally. The app's dose and injection logging lets you record every weekly shot — including dose strength, date, and injection site — so your full treatment history is always in one place. This is especially useful as doses change over time under your prescriber's guidance.
The side-effect tracker lets you log how you feel after each dose and spot patterns across weeks — information that can be genuinely valuable to bring to your next prescriber appointment. The daily check-in captures mood, energy, sleep, and food noise alongside your weight, giving you a complete picture of how your body is responding rather than just a number on the scale.
For a broader overview of how these two medicines are compared, visit our guide on Wegovy vs Mounjaro.
The decision about which injection is prescribed — or whether either is appropriate — always rests with your prescriber or doctor. GLP Trackr helps you record and understand your journey once that decision has been made; it is not a substitute for clinical advice.
Both medicines are prescribed, tracked, and supported in the app. Download GLP Trackr on the App Store or Google Play and start a free 7-day trial — log your first dose today.
What does glptrackr include?
10+ powerful features. One app. Built specifically for Mounjaro and Wegovy users.
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Morning Check-In
Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
Injection Tracking
Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
Hydration Reminders
Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
Smart Meal Planning
Personalized meal plans built around your current dose phase and side effects. Every meal is GLP-1 optimized — high in protein, gentle on the stomach, and scaled to your reduced appetite.
Recipe Library
Browse 50+ high-protein, GLP-1-friendly recipes filtered by meal type, prep time, and dietary needs. Every recipe includes full nutrition info, step-by-step instructions, and tips for eating with side effects.
Progress Analytics
Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
AI Meal Scanning
Snap a photo of any meal and get a full nutrition breakdown in seconds — calories, protein, carbs, fat, and fibre. No searching. No manual logging. Just point, snap, and track.
Exercise & Steps
Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.
Community Support
Connect with thousands of others navigating the same medication journey. Share milestones, ask questions, find accountability partners, and get support from people who truly understand.
Never Forget a Dose Again.
Log your Mounjaro or Wegovy injection in seconds. Track your pen, your dose level, and your injection site — so you always know exactly where you are in your treatment.
Watch Your Body Transform, Week by Week.
Log your weight, measurements, and how you're feeling after each dose. GLPTrackr turns your data into clear, motivating charts that show you how far you've really come.
You're Not on This Journey Alone.
Connect with thousands of real GLP-1 users sharing their wins, side effect tips, and meal ideas. Get the support of people who truly get it — because they're living it too.
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The first AI built exclusively for GLP-1 weight loss. Every insight, every meal plan, every prediction trained on one thing only: helping you get the most out of your medication.
Knows Your Cycle
GLPIQ tracks where you are in your injection cycle and adjusts everything around it: lighter meals on nausea days, higher protein when appetite returns, and smarter targets as your medication level shifts.
Predicts Before You Feel It
GLPIQ learns your personal side effect patterns over time. After a few cycles, it starts warning you the morning before a rough day — and adjusts your meal plan automatically.
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Frequently asked questions.
Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist, while Wegovy contains semaglutide, a GLP-1 receptor agonist. Both are prescription-only, once-weekly injectable medicines, but they differ in active substance, mechanism, and dose range.
Neither can be called universally better — suitability depends on your individual health history and circumstances. The right medicine for you is a decision for your prescriber or doctor, not something that can be determined from a general comparison.
Any decision to switch between Mounjaro and Wegovy must be made by your prescriber or doctor. Never start, stop, or change your medication without their guidance.
Yes. GLP Trackr supports people already prescribed either medicine. You can log doses, injection sites, side effects, weight, food, and mood regardless of which injection you have been prescribed.