How Do I Inject Mounjaro (or Wegovy)? Sites, Rotation and What to Expect

Subcutaneous injections for both Mounjaro (tirzepatide) and Wegovy (semaglutide) are typically given in one of three areas:

• Abdomen — the area around your stomach, avoiding the two inches directly around the navel
• Front of the thigh — the middle portion of the upper leg
• Upper arm — the outer, fleshy area; some people find this easier with assistance

Each of these sites has enough tissue to absorb a weekly injection safely, and all three are described in the patient information leaflets for both medicines. For specific guidance on which site suits you personally, your prescriber or doctor is the right person to ask.

Why rotation matters

Injecting repeatedly into exactly the same spot can cause changes to the skin and tissue underneath — a condition called lipohypertrophy — which may affect how the medicine is absorbed. Rotating around and between sites each week helps avoid this. A simple approach is to work around a site in a rough clockwise pattern before moving to the next site, though the exact method is less important than the habit of not reusing the same small area week after week.

A few general points to keep in mind

• Avoid injecting into skin that is bruised, tender, scarred or has visible lumps
• Allow the pen to reach room temperature before injecting — check your leaflet for the recommended time, as it varies by product
• You do not need to pinch the skin for most subcutaneous injections, but follow the instructions in your pack
• Never inject into a vein or muscle — the pre-filled pen is designed for subcutaneous use only

For a closer look at site selection, see our guides on choosing your Mounjaro injection site, Wegovy injection site guidance, and where people commonly inject Mounjaro for more detail on each area.

If you are ever uncertain about your technique or whether a site looks normal, contact your prescriber or doctor — they know your individual circumstances and can advise you directly.

Keeping track of which site you used last week — and exactly when you gave the injection — is harder than it sounds, especially once a weekly routine becomes second nature. GLP Trackr's injection-site tracking feature is designed to solve this: log the site after each injection and the app builds a rotation history, so you always know where you injected last and where to go next.

Alongside site tracking, you can log the dose strength and the date and time of each injection in one place. If your weekly schedule shifts slightly — or you are wondering whether a dose was actually given — that record is right there. The app also has gentle dose reminders, so a weekly injection is never quietly forgotten in a busy schedule.

All of that logged data becomes genuinely useful at prescriber appointments too. Rather than trying to remember details from six weeks ago, you have a clear record ready to share.

GLP Trackr is free to try for seven days and is available on the App Store and Google Play — give it a go and let it handle the rotation tracking while you focus on your journey. For a broader look at managing your weekly injections, visit our weight loss injections guide.

Your prescriber or doctor is your primary source of advice on injection technique, site care and anything that looks or feels unusual at an injection site. GLP Trackr helps you record your journey — it is not a substitute for professional clinical guidance.