Mounjaro and Wegovy: A Factual Side-by-Side
The most important distinction between the two medicines lies in their active substances and how they act in the body.
Active Substance and Mechanism
- Wegovy contains semaglutide, a GLP-1 receptor agonist. It works by mimicking the GLP-1 hormone, which is involved in regulating appetite and feelings of fullness, and slowing gastric emptying.
- Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist. It acts on both the GIP and GLP-1 pathways — a combination not found in semaglutide-based medicines.
How They Are Taken
Both medicines are given as a once-weekly subcutaneous (under the skin) injection using a pre-filled pen device. Both are typically started at a lower dose and adjusted over time, with any titration schedule determined by the prescriber — not self-managed.
Comparing with Related Medicines
Readers sometimes ask about the difference between Wegovy and Ozempic (both contain semaglutide but are licensed for different purposes), or about how Mounjaro compares with Ozempic in terms of mechanism and use. You may also find the overview on Saxenda versus Wegovy useful if you've encountered liraglutide as an option. Questions about metformin versus Mounjaro are also common — metformin is an oral medicine with a different mechanism entirely; any comparison in the context of your own treatment is a conversation for your prescriber.
What They Are Not
Neither medicine is a quick cosmetic fix, a substitute for dietary and lifestyle changes, or suitable for everyone. Suitability is assessed individually by a prescriber. According to information published on the electronic Medicines Compendium (eMC), both medicines carry a black triangle (▼) designation, meaning they are subject to additional monitoring; any side effects should be reported to your healthcare professional and, where relevant, to your national reporting scheme (such as the UK's Yellow Card scheme).
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
Tracking the right four numbers — weight, waist, protein and dose — turns a noisy chart into a clear story. That's the loop GLP-1 users keep coming back for.
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Whichever You're On, GLP Trackr Tracks It
GLP Trackr is built for people already prescribed either Mounjaro or Wegovy — the app works with both, and makes no recommendation about which medicine you should be on. That decision is your prescriber's.
The most immediately useful feature for anyone comparing their experience on either medicine is side-effect tracking: log how you feel after each dose — nausea, fatigue, energy shifts, appetite changes — and over time the app surfaces patterns you can bring to your prescriber appointments. If you've switched from one medicine to the other, or are curious how your current experience compares to what you logged before, your own data is the most honest reference you have.
Alongside that, dose and injection logging keeps a clear record of every weekly shot — date, dose strength, and injection site — so nothing gets lost across weeks or months of treatment. The app can also generate a summary to share with your prescriber, giving them a clearer picture of your journey.
GLP Trackr helps you record and understand your own experience — it isn't a substitute for your prescriber's guidance, and any questions about whether to continue, switch, or adjust your medicine should always go to your healthcare professional.
For a broader overview of how these medicines compare across multiple dimensions, see the Wegovy vs Mounjaro comparison hub.
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Morning Check-In
Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
Injection Tracking
Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
Hydration Reminders
Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
Smart Meal Planning
Personalized meal plans built around your current dose phase and side effects. Every meal is GLP-1 optimized — high in protein, gentle on the stomach, and scaled to your reduced appetite.
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Browse 50+ high-protein, GLP-1-friendly recipes filtered by meal type, prep time, and dietary needs. Every recipe includes full nutrition info, step-by-step instructions, and tips for eating with side effects.
Progress Analytics
Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
AI Meal Scanning
Snap a photo of any meal and get a full nutrition breakdown in seconds — calories, protein, carbs, fat, and fibre. No searching. No manual logging. Just point, snap, and track.
Exercise & Steps
Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.
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Connect with thousands of others navigating the same medication journey. Share milestones, ask questions, find accountability partners, and get support from people who truly understand.
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Log your Mounjaro or Wegovy injection in seconds. Track your pen, your dose level, and your injection site — so you always know exactly where you are in your treatment.
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Frequently asked questions.
Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist, while Wegovy contains semaglutide, which acts on GLP-1 receptors only. Both are once-weekly prescription-only injectables used in weight management; their differences and suitability for any individual are assessed by a prescriber.
Neither medicine can be called universally better than the other. Suitability depends on individual health history, other medications, and clinical factors that only your prescriber or doctor can assess. This comparison is informational only and does not recommend one medicine over the other.
Any decision to switch between medicines is a clinical one and must be made with your prescriber or doctor — never independently. They will consider your full health history and any other medicines you take before making that recommendation.
Yes. GLP Trackr is designed for people already prescribed either Mounjaro or Wegovy. You can log doses, track injection sites, record side effects, and monitor progress regardless of which medicine you have been prescribed.
Semaglutide mimics the GLP-1 hormone to regulate appetite and slow gastric emptying. Tirzepatide acts on both GLP-1 and GIP receptors. Both mechanisms are involved in appetite regulation; the clinical implications for any individual are a matter for their prescriber.