How Mounjaro and Wegovy Compare: Key Differences
The question of whether a Mounjaro dose is "equivalent" to a Wegovy dose comes up often, particularly when people are curious about how the two medicines relate to each other. The short answer is: they cannot be directly mapped onto one another, because they work differently and are measured in different dose strengths.
Different active substances, different mechanisms
Wegovy contains semaglutide, a GLP-1 receptor agonist. Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist. Because tirzepatide activates an additional receptor pathway, the pharmacology of the two medicines is distinct — even though both influence appetite regulation and feelings of fullness.
Different dose ranges
Wegovy is available in strengths of 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. Mounjaro is available in strengths of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. The numerical values cannot be compared directly — 7.5 mg of tirzepatide and any given dose of semaglutide are chemically different molecules at different potencies, so asking what 7.5 mg Mounjaro is equivalent to in Wegovy terms does not have a straightforward answer. Your prescriber determines the appropriate dose of whichever medicine you have been prescribed, based on your individual circumstances.
How titration works for each
With both medicines, treatment typically starts at a low dose and is increased gradually — a process known as titration — to help the body adjust. The titration schedule and the target maintenance dose are set by your prescriber, not determined by comparing the two medicines to each other. For a fuller side-by-side look at how these medicines differ, see our Mounjaro vs Wegovy informational comparison and our detailed breakdown of Mounjaro and Wegovy differences.
For general factual information on each medicine individually, you can also visit the Mounjaro overview or the Wegovy overview.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Because Mounjaro and Wegovy follow different dose schedules, keeping an accurate log of your injections matters — both for your own awareness and for conversations with your prescriber. GLP Trackr's dose and injection logging lets you record each shot: the date, the dose strength, and the injection site. You never have to rely on memory when your prescriber asks how the current dose has been feeling or when you last injected.
The app also includes side-effect tracking, so if you notice changes in how you feel after a dose — nausea, fatigue, or anything else — you can log it over time and see patterns emerge. That kind of record is genuinely useful to bring to a prescriber appointment, especially during the titration phase when your dose may be under review.
If at any point your side effects feel severe, persistent, or worrying, contact your healthcare professional promptly — do not adjust your dose or switch between medicines on your own. Any decision about dose or treatment belongs with your prescriber, who knows your full history.
GLP Trackr works whether you are on Mounjaro or Wegovy, and is built specifically for people already on a GLP-1 medicine. Give it a try — it is free for 7 days on the App Store and Google Play.
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Frequently asked questions.
Mounjaro (tirzepatide) and Wegovy (semaglutide) are not equivalent medicines. They have different active substances, different mechanisms of action, and different dose scales. They cannot be mapped onto each other dose-for-dose. Your prescriber determines the appropriate medicine and dose for you.
There is no direct Wegovy equivalent for 7.5 mg Mounjaro. The two medicines use different molecules measured at different potencies, so numerical doses cannot be compared. If you are considering a change in treatment, that conversation should happen with your prescriber or doctor.
Wegovy contains semaglutide, a GLP-1 receptor agonist. Mounjaro contains tirzepatide, which activates both GLP-1 and GIP receptors. Both are once-weekly injectables, but their mechanisms differ. Suitability and dosing for each individual is decided by a prescriber.
Any decision to switch between Mounjaro and Wegovy is a clinical one and should only be made with your prescriber or doctor. Never stop, start, or change your medication without guidance from a healthcare professional who knows your full medical history.
Yes. GLP Trackr is built for people already prescribed either Mounjaro or Wegovy. You can log doses, injection sites, side effects, weight, and food — whichever medicine you are taking. The app is available free for 7 days on the App Store and Google Play.