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Wegovy Dose Schedule: How Titration Works and What to Expect

Wegovy (semaglutide) follows a structured dose-escalation schedule that typically starts at a low dose and increases gradually over several months — always under the direction of your prescriber. The staged approach is designed to help your body adjust to the medicine and is not something to change or accelerate on your own; every step in the schedule belongs to a conversation with your prescriber or doctor.

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Wegovy Dose Schedule: How Titration Works and What to Expect

How the Wegovy Dose Schedule Typically Works

Wegovy is a once-weekly injectable medicine whose active substance is semaglutide, a GLP-1 receptor agonist. According to information in the electronic Medicines Compendium (eMC), the titration schedule commonly begins at 0.25 mg once weekly, with the dose increasing at roughly four-week intervals through 0.5 mg, 1 mg, and 1.7 mg, before reaching the standard maintenance dose of 2.4 mg. Your prescriber decides the pace and whether a step is appropriate for you — it is never a fixed rule that everyone moves up on the same timeline.

Higher-Dose Developments

Regulatory bodies in some countries have approved a higher 7.2 mg semaglutide dose formulation. In the UK, the MHRA has approved this new higher dose option. Whether this dose is relevant or available to you is entirely a matter for your prescriber; this page is informational only and cannot advise on suitability.

Comparing Wegovy and Mounjaro Dose Scales

A common question is why Wegovy doses — measured in milligrams — appear lower than Mounjaro doses. The two medicines have different active substances (semaglutide versus tirzepatide) and work through partly different mechanisms: Mounjaro acts on both GIP and GLP-1 receptors, while Wegovy acts on GLP-1 receptors only. Dose figures between the two are not directly comparable — they reflect different molecular weights, potencies, and formulations, not a simple "stronger or weaker" relationship. Any question about your individual Wegovy dose or how it relates to another medicine should go to your prescriber.

Missed Dose

If you miss a weekly Wegovy dose, do not attempt to double up or adjust your schedule yourself. Check the patient information leaflet that came with your pen for the manufacturer's specific guidance, and contact your prescriber or doctor if you are unsure what to do. The right course of action depends on how long ago the dose was due, and that decision belongs with your healthcare professional.

For a visual overview of the dose stages, see the Wegovy dose chart or read more about the 2.4 mg maintenance dose.

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Tracking Your Wegovy Schedule with GLP Trackr

Keeping an accurate record of every dose is one of the most practical things you can do on a weekly injection schedule — and it is where GLP Trackr is built to help. The app's dose-logging feature lets you record each injection as it happens: the date, time, and dose strength, so you always have a clear picture of where you are in your schedule.

Beyond logging, GLP Trackr sends gentle dose reminders so a weekly shot is never forgotten — particularly useful during the early titration stages when the routine is still new. If you do miss a dose, logging it in the app means you have a clear record to discuss with your prescriber at your next appointment, rather than trying to recall the details from memory. The app also generates a doctor report you can bring to consultations, summarising your dose history and any side effects you have logged — giving your prescriber the context they need to make decisions about your schedule.

For a broader look at how tirzepatide compares in its own titration structure, the Mounjaro dosing guide covers that journey in detail.

Any decision about your dose — when to increase, whether to hold at a stage, or what to do after a missed injection — must be made with your prescriber, never on your own. GLP Trackr helps you record and organise your journey; it is not a substitute for clinical guidance.

Ready to take the guesswork out of your weekly schedule? Download GLP Trackr on the App Store or Google Play and try it free for 7 days — your dose log, reminders, and doctor report are all waiting.

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Frequently asked questions.

Wegovy titration commonly starts at 0.25 mg once weekly and increases at roughly four-week intervals through 0.5 mg, 1 mg, and 1.7 mg, up to the 2.4 mg maintenance dose. Your prescriber sets the pace and decides what is right for you.

The standard maintenance dose of Wegovy is 2.4 mg once weekly. A higher 7.2 mg semaglutide formulation has been approved by regulators including the UK's MHRA. Whether any dose is appropriate for you is a decision for your prescriber or doctor.

Wegovy (semaglutide) and Mounjaro (tirzepatide) are different medicines with different active substances and mechanisms. Their dose figures reflect differences in molecular weight, potency, and formulation — they are not directly comparable. Your prescriber can advise on what is right for you.

Do not double up or adjust your schedule yourself. Check the patient information leaflet supplied with your pen for specific guidance, and contact your prescriber or doctor if you are unsure. The right action depends on how long ago the dose was due.

Dose increases on the Wegovy schedule typically occur at roughly four-week intervals, but the exact timing is decided by your prescriber based on how you are tolerating the medicine. Never increase your dose without your prescriber's direction.