How Wegovy and Saxenda Compare: Key Factual Differences
Both medicines work by acting on GLP-1 receptors involved in appetite regulation, helping many people feel fuller and reducing overall food intake. Beyond that shared mechanism, there are meaningful practical differences between the two.
Active substance and injection schedule
- Wegovy contains semaglutide and is injected once weekly using a pre-filled pen.
- Saxenda contains liraglutide and is injected once daily, also via a pre-filled pen.
The difference in injection frequency is one of the most practically significant distinctions for people already on either medicine — weekly versus daily dosing affects routines, site rotation, and how you stay consistent over time.
Mechanism
Both are GLP-1 receptor agonists. Wegovy acts on GLP-1 pathways; Saxenda works similarly via the same receptor type. It is worth noting that Mounjaro (tirzepatide) differs from both, as it targets both GLP-1 and GIP receptors — a dual-action mechanism not shared by semaglutide or liraglutide.
Dose strengths and titration
Both medicines are typically started at a lower dose and adjusted gradually, with the pace and target dose determined by the prescriber. The specific strengths available differ between the two; your prescriber or the patient information leaflet supplied with your medicine will detail the schedule that applies to you.
If you want a broader overview of how Wegovy works and what to expect, or are curious about what Wegovy actually is, those pages go into more depth on the semaglutide side of this comparison.
Are they interchangeable?
No — these are different medicines with different active substances, dosing schedules, and prescribing criteria. Switching between them, or between either and another GLP-1 medicine, is a clinical decision that belongs entirely with your prescriber. Never change, stop, or switch a prescribed medicine without discussing it with your healthcare professional first.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Tracking Whichever Medicine You're On with GLP Trackr
GLP Trackr is built for people already on a prescribed GLP-1 medicine — whether that's Wegovy, Saxenda, or another. Because Wegovy is weekly and Saxenda is daily, staying on top of your injection schedule looks quite different depending on which you take, and that's exactly where the app helps most.
The dose and injection logging feature lets you record each injection — date, time, dose strength, and site — so you always have a clear picture of where you are in your schedule. For a daily medicine like Saxenda, that means 365 potential log entries a year; for a weekly medicine like Wegovy, a clean weekly record. Either way, dose reminders help ensure nothing slips through. You can also log any side effects you notice and track them over time — useful data to bring to your next prescriber appointment.
GLP Trackr supports your journey regardless of which GLP-1 medicine you have been prescribed. You can also explore how the app supports people on Mounjaro if that's relevant to your situation.
If you have any questions about which medicine is right for you, or whether you should switch, always raise those with your prescriber or doctor — they have the full picture of your health history and are the right person to guide that decision. GLP Trackr records your journey; it doesn't make clinical recommendations.
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Morning Check-In
Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
Injection Tracking
Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
Hydration Reminders
Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
Smart Meal Planning
Personalized meal plans built around your current dose phase and side effects. Every meal is GLP-1 optimized — high in protein, gentle on the stomach, and scaled to your reduced appetite.
Recipe Library
Browse 50+ high-protein, GLP-1-friendly recipes filtered by meal type, prep time, and dietary needs. Every recipe includes full nutrition info, step-by-step instructions, and tips for eating with side effects.
Progress Analytics
Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
AI Meal Scanning
Snap a photo of any meal and get a full nutrition breakdown in seconds — calories, protein, carbs, fat, and fibre. No searching. No manual logging. Just point, snap, and track.
Exercise & Steps
Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.
Community Support
Connect with thousands of others navigating the same medication journey. Share milestones, ask questions, find accountability partners, and get support from people who truly understand.
Never Forget a Dose Again.
Log your Mounjaro or Wegovy injection in seconds. Track your pen, your dose level, and your injection site — so you always know exactly where you are in your treatment.
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Frequently asked questions.
Wegovy contains semaglutide and is injected once weekly, while Saxenda contains liraglutide and is injected once daily. Both are GLP-1 receptor agonists used in weight management, but they have different active substances and dosing schedules.
That is a decision for your prescriber or doctor, based on your individual medical history. Neither medicine can be recommended over the other here — your healthcare professional is best placed to advise on suitability.
Switching between prescribed medicines is a clinical decision that belongs with your prescriber. Never change, stop, or switch a medicine without discussing it with your healthcare professional first.
Yes. GLP Trackr supports people on any prescribed GLP-1 medicine. You can log daily or weekly injections, track side effects, and monitor your progress whichever medicine you have been prescribed.
Both are GLP-1 receptor agonists, so they share a mechanism of action. However, they contain different active substances — semaglutide (Wegovy) and liraglutide (Saxenda) — and are not interchangeable without prescriber guidance.
