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What Are the Injections for Weight Loss — and How Do They Work?

The two prescription injectable medicines most widely used for weight management today are Mounjaro (tirzepatide) and Wegovy (semaglutide). Both are once-weekly injections available only with a prescription, and both act on appetite-regulating pathways in the body. Which one is right for any individual person is a decision that belongs entirely with their prescriber or doctor — this page simply explains what these medicines are and how people already taking them can stay on top of their journey.

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What Are the Injections for Weight Loss — and How Do They Work?

The two injectable medicines used for weight management

Mounjaro and Wegovy are the two prescription injectable medicines most commonly associated with weight management. They are both given as once-weekly subcutaneous injections using pre-filled pens, and they both work by influencing the appetite-regulating systems in the body — though they do so in slightly different ways.

Wegovy (semaglutide)

Wegovy contains the active substance semaglutide, a GLP-1 receptor agonist. It mimics a hormone released after eating, which is involved in signalling fullness and regulating appetite. Many people report a reduction in what is sometimes called "food noise" — the persistent background preoccupation with food. Dose strengths commonly referenced are 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg, started low and adjusted by the prescriber over time.

Mounjaro (tirzepatide)

Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist — meaning it acts on two appetite-related pathways rather than one. It is also given as a once-weekly injection, with dose strengths commonly referenced at 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg, again adjusted by the prescriber. Both Mounjaro and Wegovy carry a black triangle (▼) in the UK, indicating they are subject to additional monitoring; any suspected side effects should be reported to your healthcare professional and to your national reporting scheme (such as the UK's Yellow Card scheme).

Neither medicine is insulin, a cosmetic treatment, or a substitute for clinical supervision. Suitability is always determined by a prescriber. For a broader look at how these medicines are used, see our guide to weight loss injections or explore how injections for weight loss are generally approached.

1–2%

average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*

Tracking the right four numbers — weight, waist, protein and dose — turns a noisy chart into a clear story. That's the loop GLP-1 users keep coming back for.

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Tracking your injection journey with GLP Trackr

Once you are prescribed one of these medicines, staying consistent with your weekly injection schedule matters — and that is where GLP Trackr is built to help.

The app's injection-site tracking and rotation feature is the most directly relevant tool here. Each time you inject, you log the site you used — abdomen, thigh, or upper arm — and the app tracks your rotation history and suggests where to inject next time. Rotating sites consistently is generally recommended to support skin and tissue health at injection points; the app makes that automatic rather than something you have to remember manually.

Alongside site rotation, dose logging lets you record every injection: the date, time, and dose strength, so you always have a clear record of where you are in your treatment. If you ever need to refer back — or want to bring a summary to an appointment — that information is already there. The app's dose reminders can also help make sure a weekly injection does not get overlooked in a busy schedule.

If you are curious about what distinguishes the two medicines factually, our page on what the weight loss injections are goes into more detail, and you can also read about how fat-targeted injection approaches differ from GLP-1 medicines.

Any questions about which medicine is right for you, how to adjust your dose, or how to manage any symptoms should always go to your prescriber or doctor — they know your full medical history. GLP Trackr helps you record and organise your journey; it is not a substitute for that clinical relationship.

Start logging your injections, tracking your sites, and building a clear record of your progress — GLP Trackr is free to try for 7 days on the App Store and Google Play.

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Morning Check-In
DAILY

Morning Check-In

Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.

Injection Tracking
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Injection Tracking

Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.

Hydration Reminders
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Hydration Reminders

Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.

Smart Meal Planning
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Smart Meal Planning

Personalized meal plans built around your current dose phase and side effects. Every meal is GLP-1 optimized — high in protein, gentle on the stomach, and scaled to your reduced appetite.

Recipe Library
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Recipe Library

Browse 50+ high-protein, GLP-1-friendly recipes filtered by meal type, prep time, and dietary needs. Every recipe includes full nutrition info, step-by-step instructions, and tips for eating with side effects.

Progress Analytics
ANALYTICS

Progress Analytics

Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.

AI Meal Scanning
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Snap a photo of any meal and get a full nutrition breakdown in seconds — calories, protein, carbs, fat, and fibre. No searching. No manual logging. Just point, snap, and track.

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Exercise & Steps

Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.

Community Support
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Connect with thousands of others navigating the same medication journey. Share milestones, ask questions, find accountability partners, and get support from people who truly understand.

Never Forget a Dose Again.

Log your Mounjaro or Wegovy injection in seconds. Track your pen, your dose level, and your injection site — so you always know exactly where you are in your treatment.

Never Forget a Dose Again

Watch Your Body Transform, Week by Week.

Log your weight, measurements, and how you're feeling after each dose. GLPTrackr turns your data into clear, motivating charts that show you how far you've really come.

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  • Track weight, meals, water, exercise, & sleep
  • Log doses, injection sites, & side effects
  • 60-second daily morning check-in
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  • Personalised AI meal plans & recipes
  • Golden Dose Finder AI
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The Most Advanced GLP-1 Brain Ever Built.

The first AI built exclusively for GLP-1 weight loss. Every insight, every meal plan, every prediction trained on one thing only: helping you get the most out of your medication.

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Knows Your Cycle

GLPIQ tracks where you are in your injection cycle and adjusts everything around it: lighter meals on nausea days, higher protein when appetite returns, and smarter targets as your medication level shifts.

Predicts Before You Feel It

Predicts Before You Feel It

GLPIQ learns your personal side effect patterns over time. After a few cycles, it starts warning you the morning before a rough day — and adjusts your meal plan automatically.

Finds Your Golden Dose

Finds Your Golden Dose

GLPIQ analyses every dose you've been on: weight loss rate, side effects, food noise, mood, protein adherence and tells you which dose gave you the best results. No other app does this.

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Frequently asked questions.

The two prescription injectable medicines most commonly used for weight management are Mounjaro (tirzepatide) and Wegovy (semaglutide). Both are once-weekly injections available only with a prescription, and suitability for either is determined by a prescriber or doctor.

Mounjaro contains tirzepatide, a dual GIP and GLP-1 receptor agonist, while Wegovy contains semaglutide, a GLP-1 receptor agonist. Both reduce appetite through hormonal pathways but act on different receptors. Which is appropriate for an individual is a decision for their prescriber.

Both Mounjaro (tirzepatide) and Wegovy (semaglutide) are relatively recent additions to weight-management treatment, approved in several countries in the early-to-mid 2020s. They represent a newer class of GLP-1-based injectable medicines distinct from older weight-loss treatments.

These once-weekly injections are typically administered subcutaneously — under the skin — in the abdomen, thigh, or upper arm. Rotating between sites is generally recommended. Your prescriber or the patient information leaflet that came with your pen will guide correct technique.

GLP Trackr lets you log each injection — date, dose strength, and site — and tracks your rotation history to suggest your next site automatically. Dose reminders help ensure you never miss a weekly injection. All data is stored so you can share a clear record with your prescriber.