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What Are the Best Weight Loss Injections? A Factual Guide

Tirzepatide (Mounjaro) and semaglutide (Wegovy) are the two prescription-only injectable medicines most widely discussed for weight management — both are once-weekly injections that work on appetite-regulating pathways in the body. Which one is right for any individual is a clinical decision made by a prescriber, not something to self-select. If you have already been prescribed one of these medicines, this guide explains what they are, where they are injected, and how tracking your injections can help you stay consistent throughout your journey.

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What Are the Best Weight Loss Injections? A Factual Guide

Mounjaro and Wegovy: What These Injections Are

Both Mounjaro (tirzepatide) and Wegovy (semaglutide) are prescription-only, once-weekly injectable medicines. They are not interchangeable, and suitability for either is determined by a prescriber based on your individual health history.

How they work

Semaglutide acts on GLP-1 receptors involved in appetite regulation and feelings of fullness. Tirzepatide acts on both GLP-1 and GIP receptors — a dual-action mechanism. Both are commonly described as reducing appetite and slowing stomach emptying, effects that many people on these medicines report experiencing, particularly in the earlier weeks. These effects are not universal, and individual responses vary.

Where the injections are given

Both medicines are delivered via pre-filled injectable pens, administered just under the skin (subcutaneous injection). The three sites most commonly used are the abdomen, the front of the thigh, and the upper arm. Rotating between sites with each injection is generally recommended to reduce the chance of skin reactions at any one spot — your prescriber or the patient information leaflet that came with your pen will guide you on technique.

Are these the only options?

There are other injectable medicines used in weight management, but Mounjaro and Wegovy are the two most widely prescribed for this purpose at the time of writing. For a closer look at what weight loss injections are available more broadly, or to compare specific options, see our guides on choosing between weight loss injections and what makes a weight loss injection suitable. The decision always rests with your prescriber.

Both medicines carry additional monitoring requirements and are subject to reporting of side effects through your national scheme (such as the UK's Yellow Card scheme, or the equivalent in your country). Any concerns should be raised with your healthcare professional promptly.

1–2%

average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*

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Tracking Your Injections With GLP Trackr

Whichever injectable medicine you have been prescribed, staying consistent with your weekly injection schedule — and rotating sites correctly — is one of the most practical things you can do to support your journey. GLP Trackr is built specifically for this.

Injection-site rotation, made automatic

The app's injection-site tracker lets you log each injection along with the site used — abdomen, thigh, or upper arm — and keeps a rotation history so you always know where you injected last. Rather than trying to remember which side of your abdomen you used two weeks ago, GLP Trackr surfaces that information instantly and can suggest where to inject next.

Never miss a weekly dose

Dose reminders mean your weekly schedule stays on track even during busy weeks. You can also log the dose strength and date of every injection, building a clear record of your treatment over time — useful to bring to appointments as part of your weight loss injection journey.

GLP Trackr helps you record your injections and spot patterns — it is a tracking tool, not a substitute for the guidance of your prescriber or doctor. If you have any concerns about your injection site, your dose, or how you are feeling, always contact your healthcare professional.

Ready to take the guesswork out of injection-site rotation? Download GLP Trackr on the App Store or Google Play — your first 7 days are completely free.

What does glptrackr include?

10+ powerful features. One app. Built specifically for Mounjaro and Wegovy users.

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Morning Check-In
DAILY

Morning Check-In

Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.

Injection Tracking
MEDICATION

Injection Tracking

Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.

Hydration Reminders
WELLNESS

Hydration Reminders

Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.

Smart Meal Planning
NUTRITION

Smart Meal Planning

Personalized meal plans built around your current dose phase and side effects. Every meal is GLP-1 optimized — high in protein, gentle on the stomach, and scaled to your reduced appetite.

Recipe Library
RECIPES

Recipe Library

Browse 50+ high-protein, GLP-1-friendly recipes filtered by meal type, prep time, and dietary needs. Every recipe includes full nutrition info, step-by-step instructions, and tips for eating with side effects.

Progress Analytics
ANALYTICS

Progress Analytics

Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.

AI Meal Scanning
AI

AI Meal Scanning

Snap a photo of any meal and get a full nutrition breakdown in seconds — calories, protein, carbs, fat, and fibre. No searching. No manual logging. Just point, snap, and track.

Exercise & Steps
FITNESS

Exercise & Steps

Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.

Community Support
COMMUNITY

Community Support

Connect with thousands of others navigating the same medication journey. Share milestones, ask questions, find accountability partners, and get support from people who truly understand.

Never Forget a Dose Again.

Log your Mounjaro or Wegovy injection in seconds. Track your pen, your dose level, and your injection site — so you always know exactly where you are in your treatment.

Never Forget a Dose Again

Watch Your Body Transform, Week by Week.

Log your weight, measurements, and how you're feeling after each dose. GLPTrackr turns your data into clear, motivating charts that show you how far you've really come.

Watch Your Body Transform

You're Not on This Journey Alone.

Connect with thousands of real GLP-1 users sharing their wins, side effect tips, and meal ideas. Get the support of people who truly get it — because they're living it too.

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  • Track weight, meals, water, exercise, & sleep
  • Log doses, injection sites, & side effects
  • 60-second daily morning check-in
  • AI meal scanning & barcode scanning
  • Personalised AI meal plans & recipes
  • Golden Dose Finder AI
  • Medication Clock — real-time level tracking
  • Daily Brief and predictive side effects
  • Full insights & weekly transformation cards
  • Unlimited progress photos
  • Doctor PDF export & body measurements
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Powered by GLPIQ 3.0

The Most Advanced GLP-1 Brain Ever Built.

The first AI built exclusively for GLP-1 weight loss. Every insight, every meal plan, every prediction trained on one thing only: helping you get the most out of your medication.

Knows Your Cycle

Knows Your Cycle

GLPIQ tracks where you are in your injection cycle and adjusts everything around it: lighter meals on nausea days, higher protein when appetite returns, and smarter targets as your medication level shifts.

Predicts Before You Feel It

Predicts Before You Feel It

GLPIQ learns your personal side effect patterns over time. After a few cycles, it starts warning you the morning before a rough day — and adjusts your meal plan automatically.

Finds Your Golden Dose

Finds Your Golden Dose

GLPIQ analyses every dose you've been on: weight loss rate, side effects, food noise, mood, protein adherence and tells you which dose gave you the best results. No other app does this.

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Frequently asked questions.

Mounjaro (tirzepatide) and Wegovy (semaglutide) are the two prescription-only injectable medicines most widely used for weight management. Both are once-weekly injections. Which is suitable for you is a decision made by your prescriber based on your individual health history.

Both medicines are injected just under the skin, typically in the abdomen, front of the thigh, or upper arm. Rotating between sites with each injection is generally recommended. Your prescriber or the patient information leaflet with your pen will advise on correct technique.

Yes, rotating injection sites is generally recommended to help reduce the risk of skin reactions at any one spot. Most people cycle between the abdomen, thigh, and upper arm. GLP Trackr can log each site and track your rotation history so you always know where to inject next.

Neither medicine can be called universally better — suitability depends on your individual circumstances, health history, and clinical judgement. The right choice is one your prescriber makes with you. GLP Trackr supports tracking whichever medicine you have been prescribed.

GLP Trackr lets you log each injection — including the date, dose strength, and site used — and tracks your rotation history to suggest where to inject next. Dose reminders help you stay on your weekly schedule, and your full injection log is always available to share with your prescriber.