The Active and Inactive Ingredients in Mounjaro
The key ingredient in Mounjaro is tirzepatide, a synthetic peptide that acts on both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. This dual-receptor action is what distinguishes tirzepatide from medicines that target only GLP-1 — such as semaglutide, the active substance in Wegovy. For a detailed look at how these receptors work, see our guide to what Mounjaro is and how it works.
Alongside tirzepatide, Mounjaro's solution contains inactive ingredients (excipients) whose job is to keep the medicine stable, maintain the correct pH, and make it suitable for injection. According to information published on the electronic Medicines Compendium, these typically include sodium phosphate, sodium chloride, hydrochloric acid and/or sodium hydroxide (for pH adjustment), and water for injections. Always check the patient information leaflet inside your pen's packaging for the definitive, up-to-date list — formulations can vary slightly by dose strength or region.
Mounjaro does not contain insulin, and it is not a steroid. It works by mimicking naturally occurring gut hormones rather than replacing any single hormone the body is missing.
If you are curious about the physical solution itself — including why you might notice small bubbles in the pen — our page on air bubbles in the Mounjaro pen explains what is and isn't normal. For a broader breakdown of the full ingredient list, see our dedicated Mounjaro ingredients guide.
Mounjaro carries a black triangle (▼) designation in some countries, meaning it is subject to additional monitoring. If you experience any unexpected reaction, report it to your national pharmacovigilance scheme (such as the UK's Yellow Card scheme) and speak with your healthcare professional.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Tracking How Mounjaro Affects You with GLP Trackr
Knowing what's in your pen is one piece of the puzzle — the other is understanding how your body responds to it week by week. GLP Trackr's side-effect tracker lets you log symptoms such as nausea, fatigue, or injection-site reactions each day, so you can start to see patterns over time rather than relying on memory when you next speak with your prescriber.
Alongside side-effect logging, the app's daily check-in captures your mood, energy, sleep, and appetite — a fuller picture of how tirzepatide is sitting with you at each stage of your journey. That kind of consistent record is genuinely useful to bring to a prescriber appointment, especially during the early weeks when your body is adjusting.
GLP Trackr is designed for people who are already prescribed Mounjaro or Wegovy — it supports your journey through tracking and insight, and is not a substitute for the advice of your prescriber or doctor. If you notice a reaction you are concerned about, contact your healthcare professional promptly rather than adjusting anything on your own.
Explore the full Mounjaro tracking guide to see everything GLP Trackr can help you log and understand on this medicine. Ready to start building your picture? Download GLP Trackr on the App Store or Google Play — your first 7 days are completely free.
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Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
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Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
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Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
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Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
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Frequently asked questions.
The active ingredient in Mounjaro is tirzepatide, a dual GIP and GLP-1 receptor agonist. It is a synthetic peptide that mimics gut hormones involved in appetite and blood-sugar regulation. It is not insulin.
Mounjaro's inactive excipients typically include sodium phosphate, sodium chloride, hydrochloric acid or sodium hydroxide for pH adjustment, and water for injections. Always check the patient information leaflet in your pen's packaging for the definitive list, as details can vary.
Wegovy contains semaglutide, a GLP-1 receptor agonist, while Mounjaro contains tirzepatide, which acts on both GLP-1 and GIP receptors. They are different active substances with different dose scales and cannot be directly compared mg-for-mg. Your prescriber is the right person to discuss any questions about your specific medicine.
The published ingredient list for Mounjaro does not include gluten-containing components, but for allergen queries specific to your health history, check the patient information leaflet and speak with your prescriber or pharmacist — they can advise based on your full medical background.
Yes. The full ingredient list is published on the electronic Medicines Compendium (medicines.org.uk) in Mounjaro's Summary of Product Characteristics. Your pen's patient information leaflet is also a reliable reference for the ingredients in your specific dose strength.