What is currently known about Mounjaro, Wegovy, and pregnancy
Neither Mounjaro nor Wegovy is recommended for use during pregnancy. The product information for both medicines advises that they should be discontinued before a planned pregnancy, and that if pregnancy occurs during treatment, the medicine should be stopped. This reflects the fact that there is currently limited human safety data on the use of tirzepatide or semaglutide during pregnancy, and animal studies have raised concerns at high doses.
Why these medicines are not used in pregnancy
Both Mounjaro and Wegovy act on appetite-regulating hormones — tirzepatide on both GIP and GLP-1 receptors, semaglutide on GLP-1 receptors. During pregnancy, adequate nutrition is critical for foetal development, and the appetite-suppressing effects of these medicines could interfere with that. On current evidence, the precautionary approach is to avoid exposure during pregnancy.
How long before trying to conceive should you stop?
According to the electronic Medicines Compendium (eMC) product information, available at medicines.org.uk, Wegovy (semaglutide) is recommended to be stopped at least two months before a planned pregnancy, due to its relatively long washout period. For Mounjaro (tirzepatide), the guidance in the product information should be followed — check the patient information leaflet that came with your pen, or discuss the exact timing with your prescriber, as recommendations may be updated. These timelines are set by prescribers on an individual basis; they are not a decision to make without professional input.
What if you got pregnant while taking Mounjaro or Wegovy?
If you discover you are pregnant while taking either medicine, contact your prescriber or doctor promptly. They will advise on stopping the medicine and on appropriate monitoring. This is a special-care situation — do not wait for your next scheduled appointment if you believe you may be pregnant. You can read more about what happens in this scenario on our dedicated page about falling pregnant on Mounjaro and what to do next.
Can GLP-1 medicines affect fertility?
Some people report that weight loss associated with GLP-1 treatment may influence hormonal cycles, which in some cases could affect fertility. This is an area where evidence is still developing, and any questions about fertility and these medicines should be discussed with your prescriber or doctor, who can consider your individual circumstances. For context on how Mounjaro works more broadly, see our overview of how Mounjaro works.
Important: If you are trying to conceive, pregnant, or breastfeeding, discuss this with your healthcare professional before continuing or stopping any prescribed medicine. Never stop or change your medication without their guidance.
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Frequently asked questions.
Pregnancy can occur while taking either medicine, but both are not recommended during pregnancy. Current guidance advises stopping them before trying to conceive. If you discover you are pregnant while taking Mounjaro or Wegovy, contact your prescriber or doctor promptly.
The product information for Wegovy (semaglutide) recommends stopping at least two months before a planned pregnancy, due to its long elimination period. For Mounjaro (tirzepatide), check your patient information leaflet and discuss the exact timing with your prescriber, as they will advise based on your individual situation.
If pregnancy is discovered during Mounjaro treatment, the medicine should be stopped and you should contact your prescriber or doctor straight away. They will advise on next steps and appropriate monitoring. Do not wait for a routine appointment — seek guidance promptly.
Some people report that weight changes during GLP-1 treatment may influence hormonal cycles, which could affect fertility in some cases. Evidence in this area is still developing. Speak with your prescriber or doctor about any fertility-related questions before making changes to your medication.
Current product information advises against using Mounjaro or Wegovy while breastfeeding, as it is not known whether these medicines pass into breast milk or what effect this may have. Always discuss this with your prescriber or doctor, who can weigh the risks and benefits for your individual circumstances.
