Why Mounjaro and Wegovy Are Not Recommended During Pregnancy
Both Mounjaro and Wegovy are prescription-only medicines that act on GLP-1 receptors — and in the case of tirzepatide, also on GIP receptors — to reduce appetite and support weight management. Neither medicine has been established as safe for use during pregnancy, and the electronic Medicines Compendium (eMC) product information for both advises discontinuation before or as soon as a pregnancy is confirmed.
What the guidance generally says
Clinical guidance typically recommends stopping these medicines at least one to two months before a planned pregnancy — but you should always confirm the specific timeframe with your prescriber, as recommendations can be updated. If you discover you are pregnant while already taking the medicine, contact your prescriber or doctor as soon as possible rather than making any decision about stopping on your own.
The fertility question
There is a separate but related topic worth knowing about: some people find that weight changes associated with GLP-1 medicines affect their menstrual cycle and, potentially, fertility. This does not mean the medicine is a contraceptive — unintended pregnancy can happen. If you are sexually active and do not wish to become pregnant, discussing contraception with your prescriber is an important step. You can read more about this on our page covering fertility and Mounjaro.
Reporting and monitoring
If you do become pregnant while taking either medicine, your healthcare team may ask you to report the pregnancy through your national pharmacovigilance scheme (such as the UK's Yellow Card scheme or your country's equivalent). Both medicines carry additional monitoring status, and pregnancy outcomes form part of that ongoing safety surveillance. Your prescriber or doctor will guide you on this.
For context on how these medicines work more broadly, see our guide to how Mounjaro works. If you have questions about other medicines you may be taking alongside it, our pages on taking antibiotics on Mounjaro and fasting on Mounjaro cover common related questions.
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If you have just found out you are pregnant, or think you might be, contact your prescriber or doctor promptly. Do not wait for a scheduled appointment.
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Frequently asked questions.
Contact your prescriber or doctor as soon as possible. Both Mounjaro and Wegovy are not recommended during pregnancy, and your healthcare team needs to review your treatment promptly. Do not stop or continue the medicine without their guidance.
Yes, unintended pregnancy can occur while taking these medicines. They are not contraceptives. Some people experience changes in their menstrual cycle during treatment, so discussing contraception with your prescriber is advisable if you do not wish to become pregnant.
Product information generally advises stopping several weeks before a planned pregnancy, but the specific timeframe can vary. Always confirm the guidance that applies to you directly with your prescriber or doctor, as recommendations may be updated.
Neither medicine is established as safe in pregnancy. Current clinical guidance advises against use during pregnancy. Your prescriber or doctor is the right person to advise you based on your individual circumstances and the most up-to-date information.
GLP Trackr can help you keep a record of your dose history, symptoms, and side effects to discuss with your healthcare team. It is a tracking tool, not a medical service, and any treatment decisions must be made with your prescriber or doctor.