How GLP-1 Dose Titration Generally Works
Both Mounjaro (tirzepatide) and Wegovy (semaglutide) follow a low-start, gradual-increase approach. Starting at a lower dose gives your body time to adjust and helps manage commonly reported side effects such as nausea or digestive discomfort before the dose is stepped up.
Mounjaro (tirzepatide) dose stages
Mounjaro is a dual GIP and GLP-1 receptor agonist available in several strengths — commonly 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. Titration typically begins at the lowest strength, with increases made by your prescriber at intervals they determine are appropriate for you. You can read more about the individual stages in our guide to how Mounjaro dosing is structured and our overview of the Mounjaro dose schedule.
Wegovy (semaglutide) dose stages
Wegovy is a GLP-1 receptor agonist with dose strengths commonly referenced at 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. Like Mounjaro, it is started at the lowest strength and increased gradually. For a closer look at how semaglutide dosing works for weight loss, see our page on semaglutide dosage for weight loss.
What about other substances sometimes mentioned alongside GLP-1 dosing?
Searches on this topic sometimes include substances such as berberine or L-carnitine. These are not GLP-1 receptor agonists and are not prescription GLP-1 medicines. If you have questions about supplements or other products alongside your prescribed treatment, speak with your prescriber or doctor — they can advise based on your full health picture.
Dose decisions for Mounjaro and Wegovy are always the prescriber's call. No online resource — including this one — can tell you what dose is right for you or when to increase. For a broader look at your Mounjaro treatment, visit our Mounjaro hub.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Tracking Your Doses with GLP Trackr
One of the most practical things you can do on a weekly injection schedule is keep an accurate record of every dose you take — and that is exactly where GLP Trackr starts.
The app's dose logging feature lets you record each injection with its date, time, and dose strength, so you always have a clear, timestamped history of your treatment. This is especially useful if you ever need to check when you last injected, or if you want to bring a full dose log to your next prescriber appointment.
Alongside dose logging, dose reminders help keep your weekly schedule on track — a gentle prompt so a dose is never accidentally forgotten. And if you do miss a dose, the right course of action is to check the patient information leaflet that came with your medicine and contact your prescriber or doctor for guidance; GLP Trackr can log the missed dose so you have an accurate record to discuss with them.
Over time, your dose log sits alongside your weight, side-effect, and wellbeing data in one place — giving you and your prescriber a joined-up picture of your journey rather than scattered notes.
Always follow your prescriber's or doctor's guidance on your dose — they know your full medical history and are the only person who should adjust your treatment. If you experience anything severe, persistent, or concerning, contact your healthcare professional promptly rather than adjusting your dose yourself.
Ready to keep a clear record of every injection? GLP Trackr is free to try for seven days — download it on the App Store or Google Play and start logging your doses today.
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Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
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Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
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Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
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Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
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Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.
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Frequently asked questions.
Mounjaro (tirzepatide) is commonly available in strengths from 2.5 mg up to 15 mg. Wegovy (semaglutide) ranges from 0.25 mg up to 2.4 mg. Both are started at the lowest strength and increased gradually under prescriber supervision.
Your prescriber or doctor decides when and whether to increase your dose, based on how you are responding and tolerating the medicine. You should never adjust your dose on your own — always follow their guidance.
Check the patient information leaflet that came with your medicine and contact your prescriber or doctor for advice. Do not double up or adjust your schedule without their guidance. You can log a missed dose in GLP Trackr to keep an accurate record for your appointment.
No. Berberine is not a GLP-1 receptor agonist and is not a prescription GLP-1 medicine. Mounjaro and Wegovy are prescription-only medicines with clinically established dose schedules. Speak with your prescriber about any supplements alongside your treatment.
GLP Trackr lets you log each injection with its date, time, and dose strength, and sends reminders so you never miss a weekly dose. Your full dose history is saved in one place, making it easy to review and share with your prescriber.