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How to Take a GLP-1 Medicine: What You Need to Know

GLP-1 medicines such as Mounjaro (tirzepatide) and Wegovy (semaglutide) are given as a once-weekly subcutaneous injection using a pre-filled pen. The injection is administered under the skin — typically at the abdomen, thigh, or upper arm — on the same day each week, at a dose and schedule set by your prescriber. How you use the pen, where you inject, and how you handle your device should all follow the specific guidance your prescriber or doctor gave you alongside the patient information leaflet included with your medicine.

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How to Take a GLP-1 Medicine: What You Need to Know

The Basics of Taking a GLP-1 Injectable Medicine

Both Mounjaro and Wegovy are injected subcutaneously — meaning just beneath the skin, not into a muscle or vein. Your prescriber will guide you on the correct technique; the notes below are general and informational, and are not a substitute for their instructions or the leaflet that came with your pen.

Common injection sites

The three sites most commonly used are the abdomen (stomach area, avoiding the area immediately around the navel), the front of the thigh, and the outer upper arm. Each site has a reasonably large surface area, so injections within that area should be rotated from week to week to allow the tissue to recover.

Rotating injection sites

Injecting repeatedly into exactly the same spot can cause localised skin changes. Rotating between sites — and varying the precise location within each site — helps reduce this. Many people find it useful to keep a simple record of where they last injected so they do not accidentally return to the same spot too soon. For a detailed look at taking Mounjaro specifically, or guidance on taking Wegovy, see those dedicated pages.

Timing and storage

Once-weekly medicines work best when taken on a consistent day each week. Check the leaflet that came with your pen for storage instructions — typically pens need to be refrigerated before first use, but your specific product leaflet is the definitive source for shelf life and handling. If you are ever unsure about storage or timing, contact your prescriber or pharmacist.

Oral liquid formulations

Some GLP-1 medicines are available in oral liquid form rather than as injections. If you have been prescribed one of these, see our page on how to take a GLP-1 oral liquid for guidance tailored to that format.

For a broader look at how these medicines act in the body, the page on how Mounjaro works covers the underlying mechanism in plain language.

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Tracking Your Injections with GLP Trackr

Keeping a reliable record of each injection — which site you used, the date, and the dose — takes only seconds but makes a real difference over a weekly schedule that runs for months. GLP Trackr's injection-site tracking and rotation feature logs exactly this: each time you record a shot, the app notes the site you used and suggests where to inject next, so rotation becomes automatic rather than something you have to remember.

Alongside site logging, the app's dose logging and weekly reminders mean you always know when your next injection is due and can confirm each dose has been recorded. If you ever miss a dose and want to note it to discuss with your prescriber, the app gives you a clear log to bring to that conversation — any decision about what to do sits with your prescriber, not the app.

If you experience side effects and want to track how they change week to week, GLP Trackr's side-effect tracker lets you log symptoms and spot patterns over time — useful context to share at your next appointment.

Always follow the specific instructions your prescriber or doctor gave you. If anything about your injection routine feels wrong — pain, swelling, skin changes at the site, or anything that worries you — contact your healthcare professional promptly rather than adjusting anything on your own.

Ready to keep a clear record of every dose and injection site? GLP Trackr is free to try for seven days — download it on the App Store or Google Play and see how straightforward your weekly routine can be.

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Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.

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Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.

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Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.

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Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.

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Log your Mounjaro or Wegovy injection in seconds. Track your pen, your dose level, and your injection site — so you always know exactly where you are in your treatment.

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Log your weight, measurements, and how you're feeling after each dose. GLPTrackr turns your data into clear, motivating charts that show you how far you've really come.

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Frequently asked questions.

GLP-1 medicines like Mounjaro and Wegovy are injected subcutaneously (just under the skin) once a week using a pre-filled pen. Common sites include the abdomen, thigh, and upper arm. Your prescriber and the patient information leaflet that came with your pen provide the definitive instructions for your specific medicine.

Injection sites are typically the abdomen, front of the thigh, or outer upper arm. Rotating the precise spot within and between these areas each week helps the tissue recover. Your prescriber can advise on which sites are most appropriate for you personally.

Any decision about a missed dose belongs with your prescriber or doctor — do not adjust your schedule or double up without their guidance. You can log the missed dose in GLP Trackr to keep a clear record to discuss at your next appointment, then contact your prescriber for advice.

GLP Trackr lets you log each injection — recording the site used, dose, and date. The app tracks your rotation history and suggests where to inject next. Dose reminders help you stay on your weekly schedule, and a clear log is available to share with your prescriber.

Some GLP-1 formulations are available as oral liquids rather than injections. Which form is right for you is determined by your prescriber. GLP Trackr supports tracking whichever form you have been prescribed.