How to Take Wegovy: What You Need to Know About the Pen and Injection

Wegovy is supplied as a pre-filled, single-use pen. You do not need to draw up a dose or handle a syringe — the pen is designed to deliver the dose automatically when you follow the steps described in your patient information leaflet (PIL). Always refer to the PIL that came with your pen or check the electronic Medicines Compendium (eMC) for the most accurate, up-to-date instructions for your specific pen.

Common injection sites

Three areas are commonly used for subcutaneous injections of Wegovy:

• Abdomen — the area around the stomach, avoiding the navel
• Thigh — the front or outer part of the upper thigh
• Upper arm — the outer area (often easier with assistance)

Why injection-site rotation matters

Using the same spot repeatedly can cause skin changes such as lumps or thickening (lipohypertrophy), which may affect how well the medicine is absorbed. Rotating between sites — and varying the exact location within each site — helps keep the skin healthy. Many people find it helpful to follow a simple rotation pattern so they always know where their last injection was.

Timing and consistency

Wegovy is taken once a week. Choosing a consistent day — and ideally a time that fits naturally into your routine — makes it easier to stay on schedule. If you need to shift your injection day by a day or two, your prescriber or doctor can advise on the best way to manage that; it is not a decision to make without their guidance.

For a broader look at how GLP-1 medicines are taken and how they work in the body, see our guide on taking GLP-1 medicines. If you are also interested in how tirzepatide is administered, the process shares similarities — read about how to take Mounjaro for comparison.

Keeping a clear record of every injection — which site you used, the date, and the dose — takes the guesswork out of rotation and helps you notice any patterns over time. That is exactly where GLP Trackr's injection-site tracking is most useful.

Each time you take your Wegovy shot, you can log the site and let the app suggest your next rotation automatically, so you never have to remember whether it was left thigh or right abdomen last week. Alongside site logging, the app records your dose strength and the date of each injection, giving you a clean history you can bring to your next prescriber appointment.

Dose reminders are built in too — if your injection day tends to slip your mind, a gentle weekly nudge keeps your schedule on track without you having to set anything up separately.

If you experience any side effects around the time of your injection — nausea, a reaction at the injection site, or anything else — you can log those in the same session, building a picture of how your body responds over time. That record can be genuinely useful when discussing your progress with your prescriber or doctor.

For a deeper understanding of how semaglutide works in the body, our guide to how GLP-1 medicines work covers the underlying mechanisms. You might also find it helpful to read about taking GLP-1 medicines in oral liquid form if that is relevant to your situation.

GLP Trackr is an information and tracking tool — it is not a substitute for the guidance of your prescriber or doctor. If you have any concerns about your injection technique, a reaction at the injection site, or how your medicine is affecting you, contact your healthcare professional. Any side effects worth reporting can also be submitted to your national reporting scheme (such as the UK's Yellow Card scheme) and discussed with your prescriber.

Ready to take the effort out of tracking your weekly shot? Log your injections, rotation history, and dose reminders all in one place — GLP Trackr is free to try for 7 days on the App Store and Google Play.