Mounjaro to Wegovy Dose Conversion: What You Need to Know

Mounjaro and Wegovy work differently at a pharmacological level. Mounjaro's active substance, tirzepatide, is a dual GIP and GLP-1 receptor agonist, while Wegovy's active substance, semaglutide, acts only on the GLP-1 receptor. Because they bind to different receptors with different affinities, their dose strengths are not directly comparable — a milligram figure on one pen does not translate to an equivalent milligram figure on the other.

Different dose ranges, different titration ladders

Mounjaro is typically initiated at 2.5 mg and titrated by a prescriber through strengths of 5, 7.5, 10, 12.5, and up to 15 mg on a schedule determined by individual response and tolerability. Wegovy is typically started at 0.25 mg and titrated through 0.5, 1, 1.7, and up to 2.4 mg. The numerical difference in these ranges reflects the different potency profiles of each molecule — they cannot be mapped onto each other in a simple ratio.

What this means if you are switching

If your prescriber has discussed moving you from one medicine to the other, they will not be working from a conversion chart — they will assess your history, current dose, tolerability, and any other health factors before deciding where to start you on the new medicine. Some people switching between these medications may be restarted at a low introductory dose of the new medicine rather than at any notional "equivalent" point. For a detailed look at how Wegovy's dose schedule is structured, see how the Wegovy dose schedule works, and for more on individual Wegovy dose stages, understanding your Wegovy dose has further information.

If you are specifically thinking about moving from a 7.5 mg Mounjaro dose, switching from 7.5 mg Mounjaro to Wegovy covers the considerations involved in more detail.

Any decision about switching, pausing, or adjusting your medication must be made with your prescriber — never on your own. If you have questions about your current treatment, contact your healthcare professional before making any changes.

When you move from one medicine to another, keeping an accurate record of your dose history becomes especially useful — both for your own clarity and for your prescriber appointments. GLP Trackr's dose logging feature lets you record every injection: the medicine, dose strength, date, and time, all in one place. This means your complete history travels with you whether you are on Mounjaro, Wegovy, or mid-switch between the two.

Alongside dose logging, the app's dose reminder feature helps you stay on your new weekly schedule without missing a beat during the adjustment period — particularly helpful when the injection day or pen type has changed. You can also use the side-effect tracker to log how you feel in the days after each injection, building a clear picture of your tolerability on the new medicine that you can bring to your next prescriber appointment.

For a broader overview of managing your treatment schedule, the Mounjaro dosing guide covers how dose stages are generally structured.

GLP Trackr is not a substitute for your prescriber's guidance — it is a companion for the journey they have set you on. Any concerns about your switch, your dose, or how you are feeling should always be discussed with your healthcare professional promptly.

Keep your full injection history in one place as you navigate a medication switch. Download GLP Trackr on the App Store or Google Play and start a free 7-day trial today.