Mounjaro vs Wegovy Dosage: What Are the Differences?

Both medicines start at a low introductory dose and are increased gradually over several months, a process known as titration. The pace and the dose strengths involved differ between the two.

Mounjaro (tirzepatide) dose stages

Mounjaro is commonly available in six strengths: 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg. Treatment typically begins at 2.5 mg once weekly. According to information in the electronic Medicines Compendium (eMC), the dose is then increased in 2.5 mg steps at intervals determined by your prescriber, up to a maximum of 15 mg weekly. The exact timing of each increase is a clinical decision — your prescriber will consider how you are tolerating the medicine before moving you up.

Wegovy (semaglutide) dose stages

Wegovy is available in five strengths: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. It typically starts at 0.25 mg once weekly, with the maintenance target dose being 2.4 mg weekly. As with Mounjaro, escalation is managed by your prescriber and may be slowed or paused depending on tolerability.

A quick comparison at a glance

• Starting dose: Mounjaro 2.5 mg vs Wegovy 0.25 mg
• Maximum dose: Mounjaro 15 mg vs Wegovy 2.4 mg
• Number of titration steps: Mounjaro typically 6 strengths vs Wegovy 5 strengths
• Frequency: Both once weekly
• Mechanism: Mounjaro acts on both GIP and GLP-1 receptors; Wegovy acts on GLP-1 receptors only

The dose numbers are not directly comparable between the two medicines — the active substances are different, so a higher milligram figure does not mean a stronger or weaker effect. For a broader look at how the two medicines differ beyond dosage, see our Mounjaro vs Wegovy comparison. You may also find it useful to explore our full Wegovy vs Mounjaro guide for a more detailed overview of both treatments.

Important: dose decisions — including when to increase, hold, or reduce — belong entirely with your prescriber or doctor. Never adjust your dose without their guidance.

Whichever medicine you have been prescribed, keeping an accurate record of every dose is one of the most practical things you can do to stay consistent and informed throughout your treatment.

GLP Trackr's dose logging feature lets you record the exact strength and date of each injection as you go — so there is never any uncertainty about where you are in your schedule. As your prescriber moves you through titration stages, your log builds into a clear timeline you can refer back to or share at your next appointment. The app's dose reminders help ensure a weekly injection is never missed, which matters especially when you are early in a new dose stage and building a routine around it.

If you are curious about how cost factors into the decision between treatments, our cost comparison guide for Ozempic, Mounjaro, and Wegovy covers that topic in a factual, neutral way. For context on another commonly compared medicine, the Ozempic vs Wegovy overview may also be useful reading.

GLP Trackr supports users on both Mounjaro and Wegovy — whatever your prescription, the app works around your journey. The choice of medicine, and every dose decision within it, is always a matter for your prescriber, who knows your full clinical picture. If anything about your dose or side effects concerns you, contact your healthcare professional promptly rather than adjusting anything yourself.

Ready to keep your dose history in one place? Download GLP Trackr on the App Store or Google Play and try it free for 7 days — no commitment needed.