How These Injectable Medicines Are Administered
Both Wegovy (semaglutide) and Mounjaro (tirzepatide) are given as a once-weekly subcutaneous injection — meaning the medicine is delivered just beneath the skin rather than into a muscle. They come as pre-filled pens designed to make self-injection straightforward for most people.
Common injection sites
The three areas most commonly used are the abdomen (stomach), the front of the thigh, and the upper arm. Each site has a reasonable amount of fatty tissue beneath the skin, which makes it suitable for subcutaneous delivery. Your prescriber or doctor will advise on the sites appropriate for you, and the patient information leaflet that comes with your pen is the definitive guide to technique.
Why injection-site rotation matters
Repeatedly injecting the same spot can cause the tissue to become lumpy or hardened — a condition called lipohypertrophy — which may affect how well the medicine is absorbed. Rotating between sites (and between different areas within a site) helps keep skin tissue healthy. A simple rule many people follow is to avoid the same spot for at least a week before returning to it, though your prescriber's guidance takes priority.
For a broader look at injectable weight-management medicines and how they work, see our guide to weight-loss injections. If you are comparing different injectable options, the page on slimming injections covers the landscape in more detail, and our newer injectable medicines page explains what has changed in recent years.
According to the electronic Medicines Compendium (eMC), full prescribing and administration information for each medicine is available in its Summary of Product Characteristics — always a useful reference alongside your own prescriber's advice.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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How GLP Trackr Helps You Stay on Top of Your Injections
Keeping track of where you last injected — and when — is easy to forget over weeks and months of a weekly schedule. GLP Trackr's injection-site tracking feature lets you log each site after every dose; the app then uses that history to suggest your next rotation, so you never have to remember manually where you were up to.
Alongside site tracking, the dose-logging tool records the date, time, and strength of each injection in one place. Paired with gentle weekly reminders, it means a missed dose becomes far less likely — and if you do need to discuss your schedule with your prescriber or doctor, you have a clear, dated record ready to share.
If you are curious about what these medicines typically cost through different routes, the page on slimming injection costs gives a neutral overview without quoting figures that change frequently.
Any questions about your injection technique, dose strength, or whether a site reaction needs attention should always go to your prescriber or doctor — they know your full medical history and are best placed to advise. If you notice a reaction at an injection site that is severe, spreading, or does not settle, contact your healthcare professional promptly. GLP Trackr helps you log what you observe so you can have an informed conversation; it is not a substitute for that clinical guidance.
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Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
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Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
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Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
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Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
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Frequently asked questions.
The term refers to once-weekly injectable medicines such as semaglutide (Wegovy) or tirzepatide (Mounjaro), which may be prescribed for weight management through publicly funded or private healthcare pathways. They are prescription-only and administered as a subcutaneous injection.
Common sites are the abdomen, front of the thigh, and upper arm. Your prescriber or doctor will advise which sites are right for you, and your medicine's patient information leaflet contains detailed guidance on technique.
Yes — rotating sites helps prevent lipohypertrophy, a hardening of tissue that can develop from repeated injections in the same spot and may affect absorption. Most people avoid the same exact spot for at least a week before returning to it, following their prescriber's advice.
GLP Trackr lets you log each injection site after every dose. The app tracks your rotation history and suggests your next site automatically, removing the need to remember manually where you last injected.
Mild redness or tenderness at the site is commonly reported and often short-lived. If a reaction is severe, spreading, or does not improve, contact your healthcare professional promptly. Log what you notice in GLP Trackr so you have a clear record to discuss at your next appointment.