What changes when you move from Mounjaro to Wegovy?
Mounjaro and Wegovy are both once-weekly injectable medicines used in weight management, but they work differently. Mounjaro's active substance, tirzepatide, acts on two receptors — GIP and GLP-1. Wegovy's active substance, semaglutide, acts on GLP-1 alone. In practice, both are associated with reduced appetite and increased feelings of fullness, but the mechanisms and individual responses can vary.
Different dose scales
The dose strengths are not interchangeable. Mounjaro is commonly available in strengths from 2.5 mg up to 15 mg, while Wegovy ranges from 0.25 mg up to 2.4 mg. These figures are on completely different scales and cannot be mapped to each other — your prescriber will determine what starting dose on Wegovy makes sense for you specifically, based on where you are in your current treatment.
Side-effect profiles may shift
Both medicines share a similar range of commonly reported side effects — nausea, digestive discomfort, fatigue — because they act on overlapping pathways. Some people notice a difference in how they feel after a switch; others notice little change. Neither outcome can be predicted in advance. If you experience new or worsening symptoms after a change, contact your healthcare professional promptly.
For a closer look at how the two medicines compare factually, see our Mounjaro to Wegovy overview or the more detailed guide to changing from Mounjaro to Wegovy. You can also read about the broader considerations when changing from Mounjaro to Wegovy. General context on Mounjaro is available in our Mounjaro information hub.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Tracking a medicine switch with GLP Trackr
A change in medication is a genuinely useful moment to have a clear, continuous record of your journey. GLP Trackr's dose logging lets you record every injection — medicine, dose strength, date, and time — so your history stays intact across a switch rather than starting from scratch in memory.
The side-effect tracker is particularly valuable around a transition. Logging how you feel day to day — energy levels, nausea, digestive changes, mood — means you can bring a concrete picture to your prescriber rather than trying to recall three weeks of impressions. Patterns that might be easy to miss in the moment often become visible when they're logged consistently.
If your prescriber adjusts your injection schedule or starting dose on Wegovy, dose reminders in the app keep your new weekly routine on track from day one.
Any decision about whether, when, or how to make a switch rests with your prescriber — GLP Trackr helps you record what's happening so those conversations are better informed, not replace them.
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Morning Check-In
Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
Injection Tracking
Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
Hydration Reminders
Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
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Personalized meal plans built around your current dose phase and side effects. Every meal is GLP-1 optimized — high in protein, gentle on the stomach, and scaled to your reduced appetite.
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Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
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Log walks, workouts, and movement with activity targets that flex with your energy levels. On lower-energy dose days, gentler targets keep you moving without burning out.
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Frequently asked questions.
Yes, a switch is possible, but it is a decision for your prescriber or doctor. They will assess your current dose, health history, and reasons for the change before advising on whether to switch and what dose of Wegovy to start on.
The dose scales for Mounjaro and Wegovy are completely different and cannot be directly converted. Your prescriber will determine the appropriate Wegovy starting dose based on your individual circumstances — this is not something to decide independently.
Both medicines share similar commonly reported side effects such as nausea and digestive discomfort. Some people notice a difference after switching; others do not. If new or worsening symptoms appear, contact your healthcare professional promptly.
GLP Trackr lets you log every dose and side effect continuously, so your full journey history is preserved across a medicine change. This makes it easier to discuss how you felt before and after the switch with your prescriber.
Yes. GLP Trackr is built for people on either Mounjaro or Wegovy. You can log doses, track side effects, and monitor progress whichever medicine you are currently prescribed.