How Mounjaro and Wegovy Compare: The Key Differences
Mounjaro (tirzepatide) and Wegovy (semaglutide) are both once-weekly injectable medicines prescribed for weight management, but they work through different mechanisms. Understanding those differences is informational — it does not change which one is right for you; that remains a clinical decision.
Active substance and mechanism
- Wegovy (semaglutide) is a GLP-1 receptor agonist. It acts on receptors involved in appetite regulation and feelings of fullness.
- Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist — it acts on both GIP and GLP-1 receptors, making its mechanism somewhat different from a single GLP-1 agonist.
How they are taken
Both medicines are given as a once-weekly subcutaneous injection using a pre-filled pen. Doses are typically started low and adjusted over time by a prescriber — the specific schedule is individual to each person.
Dose strengths
Mounjaro is commonly referenced at strengths of 2.5, 5, 7.5, 10, 12.5, and 15 mg. Wegovy is commonly referenced at 0.25, 0.5, 1, 1.7, and 2.4 mg. These figures are for general information only; your prescriber determines which dose is appropriate for you.
Side-effect profiles
Both medicines share a broadly similar range of commonly reported side effects — particularly gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation — reflecting their shared action on GLP-1 pathways. Both carry a black triangle (▼) in the UK, meaning they are subject to additional monitoring. If you experience side effects, report them to your healthcare professional and to your national reporting scheme (such as the UK Yellow Card scheme).
For a detailed factual side-by-side, see the Mounjaro vs Wegovy overview or the dedicated page on choosing between Mounjaro and Wegovy.
What about Ozempic?
Ozempic is also a semaglutide-based medicine — the same active substance as Wegovy — but it is licensed for a different indication. The Mounjaro vs Ozempic comparison and the page on which performs better for weight loss, Mounjaro or Ozempic, cover that question in more detail.
average weekly weight change in the first 16 weeks of Mounjaro & Wegovy use*
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Whichever You Are On, GLP Trackr Supports Your Journey
GLP Trackr is built for people already taking Mounjaro or Wegovy — so whichever medicine your prescriber has chosen for you, the app works the same way. The most immediately useful feature for most users is side-effect tracking: you can log how you feel day to day — nausea, fatigue, changes in appetite, mood — and see patterns emerge over time. That log becomes genuinely useful when you have a check-in with your prescriber, giving you something concrete to discuss rather than relying on memory.
Alongside that, the app's dose and injection logging lets you record every weekly shot — which medicine, which strength, which site — so your treatment history is always clear and in one place. And if you want to understand how your food intake, sleep, or activity might relate to how you feel, the insights and analytics tools surface those connections from your own data.
GLP Trackr does not sell, supply, or advise on medication. It is a tracking companion for the journey you are already on — and it supports both Mounjaro and Wegovy users fully.
Any questions about which medicine is right for you, or whether to switch, should always be discussed with your prescriber or doctor — they know your full medical history and are best placed to guide that decision.
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Start every day with a 60-second wellness check-in. Log how you're feeling, track nausea, appetite, energy, and mood — giving you and your care team a complete picture of how your medication is working.
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Log every dose with a single tap. Track your dose history, phase in your cycle, estimated medication levels, and upcoming injection dates — with reminders so you never miss a scheduled shot.
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Staying hydrated is especially important on GLP-1 medications. Set daily water targets, log intake throughout the day, and receive smart nudges when you're falling behind your goal.
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Beautiful, easy-to-read charts show your weight loss trajectory, weekly nutrition trends, medication responses, and wellbeing scores over time — turning raw data into genuine insights.
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Frequently asked questions.
There is no single answer — both are prescription-only medicines and the right choice depends on an individual's medical history and circumstances. That decision is made by a prescriber or doctor, not by comparing the medicines in general terms.
Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist, while Wegovy (semaglutide) is a GLP-1 receptor agonist only. Both are once-weekly injectables used for weight management, with broadly similar commonly reported side effects. Prescribers choose between them based on individual clinical factors.
Ozempic and Wegovy share the same active substance (semaglutide) but are licensed for different uses. Comparing them to Mounjaro for weight loss outcomes is a clinical question — your prescriber is best placed to advise based on your specific situation and health history.
Any decision to change, switch, or stop a prescribed medicine must be made with your prescriber or doctor. Never adjust or switch your medication without consulting your healthcare professional first.
Yes. GLP Trackr is built for people already prescribed either Mounjaro or Wegovy. You can log doses, track injection sites, record side effects, and monitor progress whichever medicine you have been prescribed.